Biographies

Though Chiyo was quite adept at poison making, she was countered with antidotes made by Hidden Leafs "slug-woman" Tsunade. This loss to Tsunade made Chiyo rather bitter in her old age. When Hidden Sand village ninja Kankurou was poisoned in battle by her grandson Sasori, she was called upon by Baki to attempt to help. She stated she couldn't help as she was too old, she would rather just see her grandson. Baki countered that was convenient since the one who hurt Kankurou was that very same man. This stirred Chiyo to action. When she examined Kankurou she stated she could not help him but Tsunade could. Baki countered that Tsunade could not leave Konoha since she was the Hokage now, but that she had sent someone in her stead.

When Temari, Kakashi, Naruto and Sakura arrived in Hidden Sand to help the village, Chiyo jumped to attack Kakashi. She mistook him for his father, Hatake Sakumo, the legendary White Fang of Konoha. Chiyo blamed Sakumo for the death of her son, apparently Sasori's father, though the number of Chiyo's sons in unknown. When her brother pointed out that Kakashi wasn't Sakumo, Chiyo tried to save face by saying she was just joking. Sakura managed to use her healing skills to save Kankurou. When Naruto and his team decided to head out to track down Akatsuki, Chiyo decided to tag along. She brought along a pair of mysterious scrolls which could be used to stop her grandson's schemes.

On their journey to save Gaara, Chiyo revealed she had sealed the Shukaku demon within Gaara. Conceivably she could have also sealed Shukaku within the two previous ninja hosts before Gaara due to her elder age. Chiyo began to regret her past mistakes and resolved to do all she could to save Gaara and her village. When they made it to the Shukaku extraction cave, Chiyo and Sakura found her grandson and fought him. Chiyo's experience and Sakura's power were enough to destroy Sasori's Hiruko form and reveal his "true" appearance within, that of his younger self 20 years earlier. It was then revealed Sasori had killed the Third Kazekage and would use him in battle as a puppet against Chiyo.

Chiyo then decided it was best to combat Sasori with the scrolls she had brought along. Chiyo used them to summon two puppets, Sasori's parents who had been made into puppets in the past. Sasori was amused by this and the parent puppets were eventually damaged. Sakura's strategy allowed her to destroy the Sandaime puppet, and her constant vigilance and assistance to Chiyo greatly impressed the older kunoichi. Chiyo was forced to pull out her ultimate technique, her ten Chikamatsu puppets which she had inherited from the first kugutsu no jutsu user.

Sasori in turn would use his legendary hundred puppet army. Chiyo focused on quality over quantity and with Sakura's help made destroyed the puppet army. Unfortunately in the process Chiyo became poisoned by one of the blades. Sasori was not finished though, escaping harm to his original puppet body, he moved to another puppet and moved to quickly kill Chiyo. Sakura jumped to protect Chiyo and took a poison katana through the stomach, critically wounding her. Chiyo was again moved by her actions, knowing their one remaining poison antidote was meant for herself, she instead gave it Sakura. She then did her final acts as a puppeteer, she quickly maneuvered the parent puppets back into the field of battle to pierce Sasori's chest container where his life essence was housed. After striking an apparent fatal blow, she turned to help Sakura.

The dying and immobilized Sasori mocked the two kunoichi but Chiyo revealed her final surprise, a reincarnation jutsu which would allow her to breathe life into the dead in exchange for her own life. A jutsu she was to have used on Sasori's dead parents as a gift to her grandson. Instead Chiyo used her powers to save the young woman who gave her life in battle to protect her, much to Sasori's amused sadness. After using her jutsu, the group were surprised by the fact Chiyo remained alive, she surmised it was because Sakura was not yet dead. Since he was defeated, Sasori gave Sakura information on Orochimaru. Chiyo then watched as her grandson fell to the ground, dead. She told Sakura she was not responsible for Sasori's death, he hesitated when the parent puppets came to strike, not moving to avoid them. Severely fatigued and weakened, Chiyo stated she still had more to do so the two kunoichi left to join the others.

Finding the dead Gaara who had been rescued by Naruto, Chiyo used her jutsu one last time. Her final act of redemption was to give up the last of her life-force to Gaara, aided by the chakra of Naruto. She died happily, passing on advice to Sakura and moved by Naruto's heart.